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复旦大学赵冰研究员作高水平学术前沿讲座

  • 王百宗
  • 2024-04-26
  • 279

2024424日,复旦大学研究员、博士生导师,南昌大学类器官研究院执行院长赵冰受邀访问我系,并在我校高新校区信智楼C301会议室作“人源类器官模拟发育与疾病”报告,此次报告由我校研究生院和信息科学技术学院联合主办、赵刚教授主持,吸引了众多师生和科研人员的关注。



在报告中,赵冰院长详细介绍了类器官技术的飞速发展,这一技术使得体外创造人体器官孪生成为可能,极大地推动了生物医学研究、新药研发和精准医疗的模型革命。他从课题组科研工作的视角出发,深入阐述了人源类器官模型在研究人体器官发育,以及内源性(遗传病、出生缺陷等)和外源性(病原感染、代谢病等)疾病致病机制及干预策略中的重要优势,并提出了类器官技术开发及应用的主要方向。



赵冰院长还特别强调了类器官作为类细胞治疗药物的应用前景,这一领域被认为是类器官技术的终极目标之一。他指出,通过精确模拟人体器官的结构和功能,类器官有望在个性化医疗和再生医学中发挥巨大作用。此外,赵冰院长还提到了多类器官协同系统的发展潜力,这样的系统可以更全面地模拟人体内的复杂相互作用,为疾病研究和药物开发提供更为精确的模型。



在报告的提问环节,赵冰院长与在场师生进行了深入的交流,解答了关于类器官技术的细节和应用方面的疑问,指出了类器官作为类细胞治疗药物是当前类器官领域的终极目标以及多类器官协同系统的巨大潜力,引起了广泛的讨论,为该场报告做了总结。赵冰院长的报告不仅为在场师生带来了最前沿的学术动态,也为类器官领域的研究提供了新的思路和方向,现场师生反响热烈,掌声雷动。本次报告深入浅出,使得在场的不同背景的学者和硕博生除了对类器官领域的发展有了长足的了解,还深刻认识到医工结合以及产业转化的关键,对自身发展具有重要意义。

赵冰院长简介:

Dr. Zhao Bing, a recipient of the National "Outstanding Young Investigator" Award, serves as the principal investigator for the National Key Research and Development Program on "Stem Cells and Their Transformational Research." His research primarily focuses on elucidating the fate determination mechanisms of adult stem cells and developing innovative strategies for organoid cultivation. Over the past five years, Dr. Zhao has authored 13 top-tier papers as the corresponding author in esteemed international journals. His groundbreaking research achievements have been recognized by Nature News and prominently featured on the Nature website's homepage.

In 2018, Dr. Zhao Bing established the Organoid Research Center at Fudan University, followed by the founding of Berzing Biotech in 2021 and the Nanchang University Organoid Research Institute in 2023. Committed to advancing the standardization and industrial application of organoid technology, he is also exploring novel pharmaceutical avenues for its utilization. Dr. Zhao has spearheaded the formulation of guidelines for various ministerial-level special projects related to organoids, such as the "Fourteenth Five-Year Plan" National Key Research and Development Program, collaborative innovation initiatives supported by the National Natural Science Foundation of China, the National Postdoctoral Innovation and Entrepreneurship Program, the Shanghai Key Project, and the Guangdong Key Project.

Furthermore, as a member of the Standardization Working Committee of the Chinese Society for Cell Biology, Dr. Zhao has played a leading role in establishing multiple standards and cultivation protocols for organoids. He is the author of the Chinese Expert Consensus on Organoid Quality Control, contributing significantly to the advancement and quality assurance of organoid research in China.