谢庆国教授、博士生导师
中国科学技术大学信息科学技术学院电子工程与信息科学系（6系）教授、合肥综合性国家科学中心人工智能研究院首席研究员。数字PET发明人，国家杰出青年科学基金获得者。
Email: qgxie@ustc.edu.cn
个人简介：
专注于探测与成像方法研究和仪器研制。
发明了多阈值数字化方法（Multi-Voltage Threshold）。应用于医疗器械、科学仪器、辐射探测、石油探井等领域。在医疗器械和科学仪器领域，解决了高速脉冲精确数字化的难题，系统性地发展了全数字、模块化的PET探测器技术以及一系列智能化成像方法，建立了完整、系统的全数字PET技术体系。带领团队完成全数字PET 科学仪器（2010）、全数字PET医疗器械（2015）、标准CMOS硅光电倍增器（2017）、脑部专用全数字PET（2019）等四个全球首创，并正在开展前沿应用探索和应用示范。
创建和领导一支国际化科研团队开展了20 余年系统性研究，全面覆盖从关键材料、核心器件、成像方法到科学仪器、医疗器械、前沿应用的完整创新链，引领数字PET成像新方向，形成了集人才培养、技术创新和产业支撑为一体的全球顶尖产学研用平台。
在IEEE Transactions on Nuclear Science，Physics in Medicine and Biology，IEEE Journal of Electron Devices Society，Nature Medicine，Nature Photonics，Nature Communications等期刊发表论文110余篇。作为发明人申请发明专利300余件，获授权100 余件，覆盖中国、美国、德国、日本等地区。获得湖北省技术发明奖一等奖（2013，2024）、日内瓦国际发明展金奖3项（2013、2017）、黄家驷生物医学工程奖技术发明一等奖（2019）、中国专利金奖（2021）、世界知识产权组织全球奖（2022）。相关工作入选“2019年中国十大科技进展新闻”、“2019年度中国医学重大进展”。被授予“科技盛典—中央电视台2019年度科技创新人物”称号。
研究方向：
一、弱光探测器件、芯片与系统
具体包括：
1、SiPM芯片设计（欢迎物理、光学、微电子、电子工程的同学报考研究生）
2、MVT Digitizer芯片设计（欢迎物理、数学、微电子、电子工程的同学报考研究生）
3、数字PET科学仪器设计（欢迎数学、软件工程、生物医学工程、电子工程的同学报考研究生）
4、图像重建（欢迎数学、物理、自动化、电子工程的同学报考研究生）
5、通用光电器件、数字器件IC设计、嵌入式系统（欢迎微电子、电子工程、光学的同学报考研究生）
深入了解：https://idil.ustc.edu.cn/32986/list.htm
二、多阈值采样理论与方法研究
部分代表性论文：
Feng Zhou, Nicola D’Ascenzo, Bo Zhang, Emanuele Antonecchia, Lei Fang, Li Ba, Min Zhang, Xiaohua Zhu, Qiong Liu, Jiazuan Ni, Giacomo Frati, Michael Kreissl, Xun Chen, Jiang Wu, and Qingguo Xie, Development and Evaluation of a Portable MVT-Based All-Digital Helmet PET Scanner, IEEE Transactions on Radiation and Plasma Medical Sciences, vol. 8, no. 3, pp. 287–294, 2024.
Yiqing Ling, Ao Qiu, Lin Wan, Fei Wang, Kezhang Zhu, Yeping Zhang, and Qingguo Xie, A Novel Peak Picking Multi-Voltage Threshold Digitizer for Pulse Sampling, IEEE Transactions on Radiation and Plasma Medical Sciences, vol. 8, no. 3, pp. 248-256, 2024.
Qiuhui Ma, Zhiyong Yang, Dengyun Mu, Min Gao, Ruilin Zhang, Lin Wan, Ao Qiu, and Qingguo Xie, In-beam PET monitoring of proton therapy: a method for filtering prompt radiation events, Physics in Medicine and Biology, vol. 69, no. 12, pp. 125006, 2024.
Lei Fang, Bo Zhang, Bingxuan Li, Xiangsong Zhang, Xiaoyun Zhou, Jigang Yang, Ang Li, Xinchong Shi, Yuqing Liu, Michael Kreissl, Nicola D’Ascenzo, Peng Xiao, and Qingguo Xie, Development and evaluation of a new high-TOF-resolution all-digital brain PET system, Physics in Medicine and Biology, vol. 69, no. 2, pp. 025019, 2024.
Ao Qiu, and Qingguo Xie, Mathematical Considerations in Energy Spectrum Recovery for Digital Energy Spectrometers, IEEE Transactions on Nuclear Science, vol. 70, no. 11, pp. 2532-2537, 2023.
Ao Qiu, Lin Wan, Yiqing Ling, and Qingguo Xie, Energy Calibration of MVT Digitizers in All-Digital Gamma Cameras, IEEE Transactions on Nuclear Science, vol. 70, no. 5, pp. 847-852, 2023.
Heejong Kim, Boris Epel, Vasughi Sundramoorthy, Hsiu-Ming Tsai, Inna Gertsenshteyn, Howard Halpern, Yuexuan Hua, Qingguo Xie, Chin-Tu Chen, and Chien-Min Kao, Development of a PET/EPRI combined imaging system for assessing tumor hypoxia, Journal of Instrumentation, vol. 16, no. 03, pp. 03031, 2021.
Chen Zeng, Rui Chen, Bingxuan Li, Peng Xiao, Wei Liu, Yu Liu, Daoming Xi, and Qingguo Xie. Evaluation of a PET detector based on SiPMs and FPGA-only MVT digitizers, Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment,vol. 990, pp. 164953, 2021.
Min Gao, Hsien-Hsin Chen, Chen Hsin Fang, Ji-Hong Hong, Ing-Tsung Hsiao, Tzu-Chen Yen, Jingfang Mao, Jiade J. Lu, Weidong Wang, Nicola D'Ascenzo, and Qingguo Xie, First Results from All-digital PET Dual Heads for In-beam Beam-on Proton Therapy Monitoring, IEEE Transactions on Radiation and Plasma Medical Sciences, vol. 5, no. 6, pp. 775-782, 2021.
Xiao Liang, Jing Li, Emanuele Antonecchia, Yiqing Ling, Zhen Li, Wenchang Xiao, Qian Chu, Lin Wan, Xia Hu, Shuangxue Han, Jarmo Teuho, Lu Wan, Peng Xiao, Chien-Min Kao, Juhani Knuuti, Nicola D’Ascenzo, and Qingguo Xie, NEMA-2008 and In-Vivo animal and plant imaging Performance of the large FOV preclinical digital PET/CT system Discoverist 180, IEEE Transactions on Radiation and Plasma Medical Sciences, vol. 4, no. 5, pp.622 -629,2020.
Nicola D’Ascenzo, Emanuele Antonecchia, Andreas Brensing, Werner Brockherde, Stefan Dreiner, Johannes Ewering, Marvin Kuhn, Andrei Schmidt, Peter vom Stein, Weidong Wang, Zhenliang Zhou, and Qingguo Xie, A Novel High Photon Detection Efficiency Silicon Photomultiplier With Shallow Junction in 0.35 μm CMOS, IEEE Electron Device Letters, Vol. 40, no. 9, pp.1471-1474, 2019.
Daoming Xi, Xiang Liu, Chen Zeng, Wei Liu, Yanzhao Li, Yuexuan Hua, Xiongze Mei, Heejong Kim, Peng Xiao, Chien-Min Kao, and Qingguo Xie, Modularized compact positron emission tomography detector for rapid system development, Journal of Medical Imaging, vol.4, no.1, pp.1-9, 2017.
Weicheng Pan, Haodi Wu, Jiajun Luo, Zhenzhou Deng, Cong Ge, Chao Chen, Xiaowei Jiang, Wan-Jian Yin, Guangda Niu, Lujun Zhu, Lixiao Yin, Ying Zhou, Qingguo Xie, Xiaoxing Ke, Manling Sui, and Jiang Tang, Cs2AgBiBr6 single-crystal X-ray detectors with a low detection limit, Nature Photonics, vol.11, no.11, pp.726, 2017.
Yuan Rong, Luo Ming, Sun Zhi, Shi Shuyue, Xiao Peng, and Xie Qingguo. RayPlus: a Web-Based Platform for Medical Image Processing.Digit Imaging, vol.30, no.2, pp.197-203, 2016.
Luyao Wang, Jun Zhu, Xiao Liang, Ming Niu, Xiaoke Wu, Chien-Min Kao, Heejong Kim, and Qingguo Xie, Performance evaluation of the Trans-PET Biocaliburn lh system: a large FOV small-animal PET system, Physics in Medicine and Biology, vol.60, no.1, pp.137-150, 2015.
Jingjing Liu, Chien-Min Kao, Shuguo Gu, Peng Xiao, and Qingguo Xie, A PET system design by using mixed detectors: resolution properties, Physics in Medicine and Biology, vol.59, no.13, pp.3517-3532, 2014.
Qingguo Xie, Yuanbao Chen, Jun Zhu, Jingjing Liu, Xi Wang, Wei Liu, Xin Chen, Ming Niu, Zhongyi Wu, Daoming Xi, Luyao Wang, Peng Xiao, Chin-Tu Chen, and Chien-Min Kao, Implementation of LYSO-PSPMT block detector with all digital DAQ system, IEEE Transactions on Nuclear Science, vol.60, no.3, pp.1487-1494, 2013.
Daoming Xi, Chien-Min Kao, Wei Liu, Chen Zeng, Xiang Liu, and Qingguo Xie, FPGA-only MVT digitizer for TOF PET, IEEE Transactions on Nuclear Science, vol.60, no.5, pp.3253-3261, 2013.
Qingguo Xie, Chien-Min Kao, Xi Wang, Ning Guo, Caigang Zhu, Henry Frisch, William W. Moses, and Chin-Tu Chen, Potentials of digitally sampling scintillation pulses in timing determination in PET, IEEE Transactions on Nuclear Science, vol. 56, no. 5, pp. 2607-2613, 2009.
Qingguo Xie, Chien-Min Kao, Zekai Hsiau, and Chin-Tu Chen, A new approach for pulse processing in Positron Emission Tomography, IEEE Transactions on Nuclear Science, vol. 52, no. 4, pp. 988-995, 2005.
